During January and February 2025, Ismael Castañón carried out research at Hylomorph as part of a collaborative project between Hylomorph (Switzerland) and SetLance (Italy), focused on the development of dual-affinity peptides designed to interact with biomaterials. The peptides are based on the antimicrobial peptide SET-M33, a compound known for its potent antibacterial properties.
Castañón’s work involved a combination of in vitro experiments and computational simulations aimed at optimizing the efficacy and material-binding capabilities of novel peptide analogs. As part of the experimental phase, Alessia Maranesi and Ana Laura Pereira contributed to studies evaluating the antimicrobial activity of the new peptides against bioluminescent bacteria, helping to assess their potential as advanced biomaterial coatings.
